How fast do bisphosphonates work?

How quickly do bisphosphonates work? It takes several months for bisphosphonates to work. Usually there is an increase in bone density 6-12 months after you start taking one. This then helps to prevent breaks (fractures) of the spine, the hip, and other bones such as the wrist.

It may take 3 months or longer before your bone density begins to increase. Alendronate helps to treat and prevent osteoporosis only as long as it is taken regularly.

Additionally, how long do bisphosphonates stay in your system? An FDA review of clinical studies measuring the effectiveness of long-term bisphosphonates use shows that some patients may be able to stop using bisphosphonates after three to five years and still continue to benefit from their use, says Marcea Whitaker, M.D., a medical officer at FDA’s Center for Drug Evaluation and

Just so, are bisphosphonates really effective?

Bisphosphonates have been shown to be safe and effective for up to 10 years of treatment, depending on the medication. However, even if you stop taking the medication, its positive effects can persist. That’s because after taking a bisphosphonate for a period of time, the medicine remains in your bone.

Does alendronate cause weight gain?

Interestingly, other studies in rats have shown that alendronate treatment results in higher body weight compared with OVX [28]. One possibility of the increased weight gain could be the neo-formation of bone tissue [41].

Are bananas good for osteoporosis?

There’s a good chance the majority of it comes from salt, so the lower the sodium, the better for bones. If you think you can’t lower your salt sufficiently, eat plenty of potassium-rich foods, such as bananas, tomatoes, and orange juice. Potassium may help decrease the loss of calcium.

Can you sit down after taking Fosamax?

Do not take alendronate if you cannot sit upright or stand for at least 30 minutes. Alendronate can cause serious problems in the stomach or esophagus. You must stay upright for at least 30 minutes after taking this medicine.

Does alendronate cause hair loss?

Less common side effects of alendronate include: Hair loss.

What is the best and safest drug for osteoporosis?

Some bisphosphonates, such as Fosamax (alendronate) and Actonel (risedronate), are taken as a daily or weekly tablet, while Boniva (ibandronate) is taken monthly to prevent and treat osteoporosis. Reclast (zoledronic acid) is taken intravenously once a year to treat osteoporosis and every two years to help prevent it.

Why can’t you lay down after taking alendronate?

Do not lie down again after taking the medicine. Alendronate can cause damage to the esophagus (food pipe) and the water will wash the medication down into the stomach. If you lie down the medication might come back up into the esophagus, so that is why you should not lie down.

Why is alendronate taken once a week?

Administering alendronate (70 mg) once a week effectively provides continuous inhibition of bone resorption because bone resorption by osteoclasts is a slow process that typically requires 2-3 weeks for completion and alendronate remains at active bone remodelling sites for a sustained period and (when present in

Should I take calcium with Fosamax?

Alendronate and calcium carbonate should not be taken orally at the same time. You should take calcium carbonate at least 30 minutes after the alendronate dose.

Are bisphosphonates bad for you?

Bisphosphonates can cause problems with the jaw or thigh bone. But most women do not have these side effects. They seem to be more likely if women take bisphosphonates for more than 5 years. Whether you take medicine or not, healthy habits can help protect your bones.

What are the alternatives to bisphosphonates?

In recent years, the drug denosumab (Prolia) has emerged as an alternative to bisphosphonates for the treatment of postmenopausal osteoporosis. Denosumab may be considered a first-line treatment for women with osteoporosis who are at high risk of fracture or in women who can’t take bisphosphonates.

Which fruit is best for bones?

Good-for-Your-Bones Foods Food Nutrient Canned sardines and salmon (with bones) Calcium Fatty varieties such as salmon, mackerel, tuna and sardines Vitamin D Fruits and vegetables Collard greens, turnip greens, kale, okra, Chinese cabbage, dandelion greens, mustard greens and broccoli. Calcium

Can you rebuild bone density?

But they’re especially important for women with low bone density. While you can never regain the bone density you had in your youth, you can help prevent rapidly thinning bones, even after your diagnosis. Here’s a breakdown of five lifestyle steps to help you on the road to better bone health.

What is the safest bisphosphonate?

In randomized controlled trials (RCTs), alendronate, risedronate, and zoledronate have shown to reduce the risk of vertebral, nonvertebral, and hip fractures, whereas RCTs with ibandronate show antifracture efficacy at vertebral sites. Bisphosphonates are generally well tolerated and safe.

Is walking good for osteoporosis?

Weight-bearing Exercise for Osteoporosis That’s because you are being held up by something other than your feet and legs, such as the bicycle or the water. Walking as little as three to five miles a week can help build your bone health.

Which bisphosphonate is best?

We suggest alendronate or risedronate as the initial choice of oral bisphosphonate. Alendronate — Alendronate is effective for both the treatment and prevention of osteoporosis in postmenopausal women.